Methadone and Buprenorphine: Clinical Impact of Drug Interactions


Elinore McCance-Katz, MD, PhD
Chief Medical Officer
Substance Abuse and Mental Health Services Administration
 
Tuesday, March 11, 2014

Drug-drug interactions between opioid medications used to treat opioid dependence, such as methadone and buprenorphine, and medications for treating co-occurring physical or mental health conditions can be a source of morbidity and mortality.  This presentation will briefly review the epidemiologic data on drug-drug interactions that include methadone or buprenorphine and discuss the physiological basis for such interactions including pharmacokinetic and/or pharmacodynamics interactions.  It will also review drug-drug interactions and clinical consequences using a series of case studies that address questions related to issues of drug interactions in practice.  

Download webinar slides.